Nerve Detection in Ultrasound Images Using Median Gabor Binary Pattern

International audienceUltrasound in regional anesthesia (RA) has increased in pop-ularity over the last years. The nerve localization presents a key step for RA practice, it is therefore valuable to develop a tool able to facilitate this practice. The nerve detection in the ultrasound images is a challeng-ing task, since the noise and other artifacts corrupt the visual properties of such kind of tissue. In this paper we propose a new method to address this problem. The proposed technique operates in two steps. As the me-dian nerve belongs to a hyperechoic region, the first step consists in the segmentation of this type of region using the k-means algorithm. The second step is more critical; it deals with nerve structure detection in noisy data. For that purpose, a new descriptor is developed. It combines tow methods median binary pattern (MBP) and Gabor filter to obtain the median Gabor binary pattern (MGBP). The method was tested on 173 ultrasound images of the median nerve obtained from three patients. The results showed that the proposed approach achieves better accuracy than the original MBP, Gabor descriptor and other popular descriptors

Managing alternative sports: new organisational spaces for the diffusion of Italian parkour

The article explores the encounter between parkour as an unstructured and culturally innovative practice, challenging both physical as well as organisational spaces, and UISP (Unione Italiana Sport per Tutti / Sport for All Italian Union) as a sport promotion body open to organisational and cultural experimentation. Drawing on a multi-method qualitative approach (analysis of documentary material, interviews and focus groups), we look at the role of UISP in the diffusion and legitimation of parkour within the Italian context, investigating the interplay between the cultural and organisational logics of both this new practice itself on the one hand, and the organisations that are trying to accommodate it on the other. The incorporation in a sport-for-all organisation like UISP provides traceurs with a safe and legitimised space, which is however ‘loose’ enough to maintain the fluidity of the practice. Nonetheless, by enabling the coexistence of different and competing definitions and uses of parkour, this fluid organisational space reproduces tensions among traceurs and weakens their voice in UISP’s decision-making processes

Isoflurane cracks the polycarbonate connector of extra-corporeal circuit -A case report-

Cardiopulmonary bypass (CPB) is widely used for cardiac surgery by virtue of its proven safety over the course of its use during the past half century. Even though perfusion is safer, incidents still occur. During the repair of a ventricular-septal defect in an 11-month-old infant, we experienced a critical incident related to the potential hazardous effect of volatile anesthetics on the polycarbonate connector of extra-corporeal circuit. The damage to the polycarbonate connector had occurred after spillage of isoflurane during the filling of the vaporizer, causing it to crack and leak. The incident was managed by replacement of the cracked connector during a temporary circulatory arrest. The patient was hypothermic and the time off bypass was less than 1.5 min. There were no neurologic sequelae, the patient made an uneventful recovery. In conclusion, the spillage of volatile anesthetics can cause cracks in the polycarbonate connector of the extra-corporeal circuit, leading to potentially interruption of CPB

In Vivo Selection of a Computationally Designed SCHEMA AAV Library Yields a Novel Variant for Infection of Adult Neural Stem Cells in the SVZ

Directed evolution continues to expand the capabilities of complex biomolecules for a range of applications, such as adeno-associated virus vectors for gene therapy; however, advances in library design and selection strategies are key to develop variants that overcome barriers to clinical translation. To address this need, we applied structure-guided SCHEMA recombination of the multimeric adeno-associated virus (AAV) capsid to generate a highly diversified chimeric library with minimal structural disruption. A stringent in vivo Cre-dependent selection strategy was implemented to identify variants that transduce adult neural stem cells (NSCs) in the subventricular zone. A novel variant, SCH9, infected 60% of NSCs and mediated 24-fold higher GFP expression and a 12-fold greater transduction volume than AAV9. SCH9 utilizes both galactose and heparan sulfate as cell surface receptors and exhibits increased resistance to neutralizing antibodies. These results establish the SCHEMA library as a valuable tool for directed evolution and SCH9 as an effective gene delivery vector to investigate subventricular NSCs

Multifrequency Observations of the Gamma-Ray Blazar 3C 279 in Low-State during Integral AO-1

We report first results of a multifrequency campaign from radio to hard X-ray energies of the prominent gamma-ray blazar 3C 279 during the first year of the INTEGRAL mission. The variable blazar was found at a low activity level, but was detected by all participating instruments. Subsequently a multifrequency spectrum could be compiled. The individual measurements as well as the compiled multifrequency spectrum are presented. In addition, this 2003 broadband spectrum is compared to one measured in 1999 during a high activity period of 3C 279.Comment: 4 pages including 6 figures, to appear in: 'Proc. of the 5th INTEGRAL Workshop', ESA SP-552, in pres

Research note: residential distance and recreational visits to coastal and inland blue spaces in eighteen countries

Varied categorisations of residential distance to bluespace in population health studies make comparisons difficult. Using survey data from eighteen countries, we modelled relationships between residential distance to blue spaces (coasts, lakes, and rivers), and self-reported recreational visits to these environments at least weekly, with penalised regression splines. We observed exponential declines in visit probability with increasing distance to all three environments and demonstrated the utility of derived categorisations. These categories may be broadly applicable in future research where the assumed underlying mechanism between residential distance to a blue space and a health outcome is direct recreational contact.info:eu-repo/semantics/publishedVersio

Associations between green/blue spaces and mental health across 18 countries

Living near, recreating in, and feeling psychologically connected to, the natural world are all associated with better mental health, but many exposure-related questions remain. Using data from an 18-country survey (n= 16,307) we explored associations between multiple measures of mental health (positive well-being, mental distress, depression/anxiety medication use) and: (a) exposures (residential/recreational visits) to diferent natural settings (green/inland-blue/coastalblue spaces); and (b) nature connectedness, across season and country. People who lived in greener/ coastal neighbourhoods reported higher positive well-being, but this association largely disappeared when recreational visits were controlled for. Frequency of recreational visits to green, inland-blue, and coastal-blue spaces in the last 4 weeks were all positively associated with positive well-being and negatively associated with mental distress. Associations with green space visits were relatively consistent across seasons and countries but associations with blue space visits showed greater heterogeneity. Nature connectedness was also positively associated with positive well-being and negatively associated with mental distress and was, along with green space visits, associated with a lower likelihood of using medication for depression. By contrast inland-blue space visits were associated with a greater likelihood of using anxiety medication. Results highlight the benefts of multi-exposure, multi-response, multi-country studies in exploring complexity in nature-health associations.info:eu-repo/semantics/publishedVersio

Generalised Pose Estimation Using Depth

Estimating the pose of an object, be it articulated, deformable or rigid, is an important task, with applications ranging from Human-Computer Interaction to environmental understanding. The idea of a general pose estimation framework, capable of being rapidly retrained to suit a variety of tasks, is appealing. In this paper a solution isproposed requiring only a set of labelled training images in order to be applied to many pose estimation tasks. This is achieved bytreating pose estimation as a classification problem, with particle filtering used to provide non-discretised estimates. Depth information extracted from a calibrated stereo sequence, is used for background suppression and object scale estimation. The appearance and shape channels are then transformed to Local Binary Pattern histograms, and pose classification is performed via a randomised decision forest. To demonstrate flexibility, the approach is applied to two different situations, articulated hand pose and rigid head orientation, achieving 97% and 84% accurate estimation rates, respectively